Epithelial Cell Adhesion Molecule

A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.

Also Known As:

Antigen, CD326; CD326 Protein; ESA Antigen; Ep-CAM; EpCAM; Epithelial Specific Antigen; GA 733 Tumor-Associated Antigen; GA733 Antigen; GA733 Tumor-Associated Antigen; Tacstd1 Protein; Tumor-Associated Antigen GA733; Antigen, ESA; Antigen, Epithelial Specific; Antigen, GA733; CD326 Antigen; GA 733 Tumor Associated Antigen; GA733 Tumor Associated Antigen; GA733, Tumor-Associated Antigen; Tumor Associated Antigen GA733; Tumor-Associated Antigen, GA733

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Epithelial Cell Adhesion Molecule: 2434
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Epithelial Cell Adhesion Molecule: 2434
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Epithelial Cell Adhesion Molecule: 2434
Biological Factors: 2560
- Antigens: 145631
  - Neoplasm Antigens: 6292
    - Epithelial Cell Adhesion Molecule: 2434
  - Surface Antigens: 5857
    - Cell Adhesion Molecules: 4912
      - Epithelial Cell Adhesion Molecule: 2434

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Disease

Drug/Important Bio-Agent (IBA)